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1.
J Clin Med ; 12(9)2023 Apr 23.
Artigo em Inglês | MEDLINE | ID: mdl-37176502

RESUMO

(1) Objective: To determine whether recent advances in lung transplantation (LT) have reduced the incidence and changed the risk factors for airway complications (AC). (2) Methods: Retrospective analysis of patients receiving a lung transplant between January 2007 and January 2019. An AC was defined as a bronchoscopic abnormality in the airway, either requiring or not requiring an endoscopic or surgical intervention. Both univariable and multivariable analyses were performed to identify risk factors for AC. (3) Results: 285 lung transplants (170 single and 115 bilateral lung transplants) were analysed, comprising 400 anastomoses at risk. A total of 50 anastomoses resulted in AC (12%). There were 14 anastomotic and 11 non-anastomotic stenoses, 4 dehiscences, and 3 malacias. Independent predictors for AC were: gender male (OR: 4.18; p = 0.002), cardiac comorbidities (OR: 2.74; p = 0.009), prolonged postoperative mechanical ventilation (OR: 2.5; p = 0.02), PaO2/FiO2 < 300 mmHg at 24 h post-LT (OR: 2.48; p = 0.01), graft infection (OR: 2.16; p = 0.05), and post-LT isolation of Aspergillus spp. (OR: 2.63; p = 0.03). (4) Conclusions: In spite of advances in lung transplantation practice, the risk factors, incidence, and lethality of AC after LT remains unchanged. Graft dysfunction, an infected environment, and the need of prolonged mechanical ventilation remain an Achilles heel for AC.

5.
Transplant Proc ; 52(2): 584-586, 2020 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-32037063

RESUMO

Post-thoracotomy wound dehiscence after a lung transplant carries with it morbidity in the postoperative period. While this complication has been widely reported in the literature after a clamshell incision, the thoracotomy dehiscence's surgical solution has not received much emphasis. We present an original technical solution to deal with this complication, performed successfully in a 62-year-old woman diagnosed as having idiopathic pulmonary hemosiderosis after a single lung transplant. This surgical treatment consists of necrotic rib tissue removal, pleural effusion drainage, pulmonary adhesion removal, and chest wall defect reparation with bioabsorbable mesh. This operative technique results safe and effective for thoracotomy dehiscence reparation.


Assuntos
Transplante de Pulmão/efeitos adversos , Procedimentos de Cirurgia Plástica/métodos , Deiscência da Ferida Operatória/etiologia , Deiscência da Ferida Operatória/cirurgia , Toracotomia/efeitos adversos , Feminino , Humanos , Transplante de Pulmão/métodos , Pessoa de Meia-Idade , Próteses e Implantes , Procedimentos de Cirurgia Plástica/instrumentação , Toracotomia/métodos
6.
Transplant Proc ; 52(2): 596-598, 2020 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-32061425

RESUMO

Anastomotic airway complications after lung transplantation affect up to 20% of patients. Bronchial stenosis is the most frequent complication, while dehiscence of bronchial anastomosis is a rarely seen complication, with report incidences between 1% and 10%. Despite its low incidence, dehiscence of bronchial anastomoses remains a disastrous complication in the posttransplantation period without a well-established management protocol. We present a challenging case of complete bronchial dehiscence after unilateral lung transplantation in a patient with interstitial lung fibrosis (ILF) that occurred on postoperative day 10. The dehiscence was diagnosed early and the patient's status was stable for repeat thoracotomy, therefore, an early surgical approach was preferable to conservative management or bronchoscopy. Aggressive early surgical management in a stable patient allows for complete debridement with removal of the detritus that impedes correct anastomosis healing and permits the removal of microbial vegetations with successful results.


Assuntos
Brônquios/cirurgia , Transplante de Pulmão/efeitos adversos , Complicações Pós-Operatórias/cirurgia , Deiscência da Ferida Operatória/cirurgia , Anastomose Cirúrgica/efeitos adversos , Brônquios/patologia , Humanos , Masculino , Pessoa de Meia-Idade , Complicações Pós-Operatórias/etiologia , Deiscência da Ferida Operatória/etiologia
9.
Eur J Cardiothorac Surg ; 57(6): 1221-1223, 2020 06 01.
Artigo em Inglês | MEDLINE | ID: mdl-31747002

RESUMO

Tracheobronchomegaly or Mounier-Kuhn syndrome is a rare disorder characterized by the widening of the trachea and the main bronchi. It is a form of tracheomalacia called 'cartilaginous malacic' and is characterized by deformation of the tracheal cartilages and intrusion of the redundant membranous wall into the lumen of the airway. We present a patient with Mounier-Kuhn syndrome managed like patients with tracheomalacia of other aetiologies-a tracheobronchoplasty with a reconstructed D-shaped trachea and stabilization of the posterior membranous wall by attaching a polypropylene mesh to the posterior membranous wall of the trachea and the main bronchi after a trial period with a tracheobronchial Y-shaped silicone stent.


Assuntos
Traqueobroncomegalia , Brônquios/diagnóstico por imagem , Brônquios/cirurgia , Humanos , Silicones , Stents , Traqueia/diagnóstico por imagem , Traqueia/cirurgia , Traqueobroncomegalia/diagnóstico por imagem , Traqueobroncomegalia/cirurgia
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